Mollusk
Cultivated mollusk meat — mussels, scallops, oysters, and snails — is an early-stage cell-ag category. This page collects the fixed data artifacts relevant to cultivating mollusk cells: transcriptomic and proteomic deposits spanning muscle tissue analysis, adductor-muscle differentiation, toxin response, and molecular-resource development across bivalves and gastropods. No GTEx-style atlas or genome-scale metabolic model exists for any mollusk yet; the data here is individual study deposits.
Muscle tissue transcriptomics & differentiation
The mollusk muscle datasets are predominantly comparative transcriptomics across tissues and muscle types. RNA-seq of mantle, muscle, and gill in the Mediterranean mussel (SRP033481) and of foot muscle versus mantle in the giant triton snail (PRJNA695322) characterise tissue-specific expression, while a fast- vs slow-muscle proteomic/transcriptomic study in the Yesso scallop and a microRNA signature of its striated versus smooth adductor muscles (PRJNA822005) probe muscle-type differentiation — relevant background for any cultivated-mollusk muscle-tissue work.
Toxin response & molecular-resource development
Two further datasets sit outside the muscle focus: an RNA-seq profile of the queen scallop digestive gland after exposure to domoic-acid-producing algae (PRJNA508885), relevant to contamination and food-safety screening; and an early RNA-seq-based molecular-resource effort for the freshwater mussel Villosa lienosa (SRP009061), a reference-building dataset for a species with little prior sequence data.
Complete data inventory
A curated snapshot. NCBI / ProteomeXchange accessions are the canonical living source — fetch the linked accession for current sample counts, file sizes, and availability.
| Study | Type | Species | Tissue | Description | Size | Area of research |
|---|---|---|---|---|---|---|
| RNA-Seq in Mytilus galloprovincialis: comparative transcriptomics among different tissues | RNA-seq | Mytilus galloprovincialis | Mantle, Muscle, Gill | Mantle, muscle, and gill from 5 mussels; 2 biological replicates per tissue (gill: 1) | 33.7 Gb | Muscle tissue analysis |
| Differences between fast and slow muscles in scallops revealed through proteomics and transcriptomics | RNA-seq, mass spectrometry | Patinopecten yessoensis | Muscle | Transcriptomic and proteomic, 2 biological replicates, 6 individuals; SRA run SRR4254476 marked unavailable in source — proteomics linked via ProteomeXchange PXD005166 | ~94 M reads | Muscle tissue analysis |
| Rapid development of molecular resources for the freshwater mussel Villosa lienosa | RNA-seq, contigs | Villosa lienosa | Mantle, Muscle, Gill | RNA-seq of 4 samples; also GenBank contigs JR494687–JR540729 | 16.2 Gb | Molecular-resource development |
| RNA-Seq transcriptome profiling of the queen scallop digestive gland after domoic-acid exposure | RNA-seq | Aequipecten opercularis | Digestive gland | Digestive-gland transcriptome after exposure to domoic-acid-producing Pseudo-nitzschia | ~968 M filtered reads | Toxin response |
| Comparative transcriptomic profiles between foot muscle and mantle in the giant triton snail | RNA-seq | Charonia tritonis | Muscle, Mantle | Foot muscle and mantle tissue from adult C. tritonis | 7 Gb | Muscle tissue analysis |
| MicroRNA expression signature in the striated and smooth adductor muscles of the Yesso scallop | miRNA-seq | Patinopecten yessoensis | Muscle | Striated and smooth adductor-muscle tissue from young adults | 4 Gb | Muscle growth & differentiation |
Curation source: The deposit entries above were initially curated from the supplemental Table 1 of Todhunter et al. 2024 (Papers.md ref #132). Subsequent additions come from CAAIL contributors.
Further reading
- Adjacent research areas: Cellular Engineering, Bioprocess Control, Media Optimization.
- Sequence & expression repositories: GEO, SRA, Ensembl — the canonical living indexes for the deposits curated here.
- Alternative-seafood species references: Seafood Species Reference Databases in
Databases.md. - Cross-species modeling tooling: TranscriptFormer and UCE in
Software.md— relevant where labelled mollusk data is sparse. - Reference substrates: HumanReference, CHOReference, CrossSpecies. AI/ML benchmarks: Benchmarks.