Sheep / Ovis aries
Cultivated lamb is an early-stage cell-ag target. Systems-level data for Ovis aries is beginning to accumulate — most notably a multi-tissue atlas of genetic regulatory effects within the FarmGTEx family. Dedicated cultivated-lamb cell datasets remain sparse, but a cluster of conventional ovine meat-quality proteomics and metabolomics — catalogued below — offers reference substrate for the sensory- and quality-prediction problems cultivated lamb will share, and the page will grow as the field’s data accumulates.
Featured atlases
SheepGTEx-Portal
Sheep sub-portal of the FarmGTEx consortium, providing multi-tissue regulatory-effects maps across sheep (Ovis aries) tissues — extending the FarmGTEx pattern from cattle, pig, and chicken into the small-ruminant lineage and a regulatory-genomics substrate for cultivated-lamb cell-line characterisation. Companion to Papers.md ref #138 (Gong et al. 2025, bioRxiv). Full entry in Databases.md / Livestock Multi-Tissue Atlases.
Postmortem proteome & meat-quality omics
Ahead of dedicated cultivated-lamb cell datasets, a cluster of conventional ovine meat-quality omics studies — surfaced by walking the Encyclopedia of Meat Sciences omics reviews — provides reference substrate for the sensory- and quality-prediction problems cultivated lamb will share. A redox proteome of Tan mutton under low-temperature storage (Tao et al. 2021, LWT) catalogues 1,089 proteins carrying differentially changed oxidation sites; a roasting proteome of lamb longissimus thoracis et lumborum (Yu et al. 2016, Meat Science) tracks protein-profile and amino-acid-residue modifications with cooking; and a HILIC-MS metabolome of colour-stable versus colour-labile ovine longissimus (Subbaraj et al. 2016, Meat Science) maps the small-molecule basis of meat-colour stability. None deposited to a repository — each study’s full data table lives in its supplementary materials.
Complete data inventory
A curated snapshot. Each entry’s data lives in the linked paper’s supplementary materials (no repository deposit) — fetch the source for the full table.
| Study | Type | Tissue | Description | Size | Area of research |
|---|---|---|---|---|---|
| Proteomics analysis to investigate the effect of oxidized protein on meat color and water holding capacity in Tan mutton under low temperature storage | LC-MS/MS redox proteomics | Muscle | Tan mutton under −2/−4/−18 °C storage versus fresh control (Tao et al. 2021, LWT); full list of 1,089 proteins with differentially changed oxidation sites in Supplementary Table 1 — supplementary data, not a repository deposit | — | Redox proteome & meat quality |
| Proteomic investigation of protein profile changes and amino acid residue-level modification in cooked lamb longissimus thoracis et lumborum: the effect of roasting | LC-MS/MS proteomics | Muscle (longissimus thoracis et lumborum) | Lamb LTL roasted 0/5/10 min (Yu et al. 2016, Meat Science); full per-run protein-identification reports and annotated MS/MS spectra of heat-modified peptides in Supplementary data 2–3 — supplementary data, not a repository deposit | — | Cooking proteomics |
| A hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) based metabolomics study on colour stability of ovine meat | HILIC-MS metabolomics | Muscle (loin / longissimus) | Colour-stable versus colour-labile ovine loin (longissimus) under MAP/VAC packaging (Subbaraj et al. 2016, Meat Science); full detected-metabolite table (m/z, retention time, ionisation mode, confidence level, fold-change) in Supplementary Table S1 — supplementary data, not a repository deposit | — | Colour-stability metabolomics |
Curation source: These ovine meat-quality omics entries were curated by walking the cited references of the Encyclopedia of Meat Sciences (2024) reviews on proteomics (Gagaoua et al. 2024) and metabolomics (Kiyimba et al. 2024) in meat research. Contributions of further Ovis aries datasets relevant to cultivated meat are welcome — see CONTRIBUTING.md.
Further reading
- Atlases & functional genomics: SheepGTEx-Portal (featured above), FarmGTEx, and FAANG in
Databases.md. Foundational reference: Papers.md ref #138 (Gong et al. 2025, A multi-tissue atlas of genetic regulatory effects in sheep, bioRxiv). - Sequence & expression repositories: GEO, SRA, Ensembl (Ovis aries genome assembly).
- Cross-species modeling tooling: TranscriptFormer and UCE in
Software.md— especially useful where labelled species data is sparse. - Adjacent research areas: Cellular Engineering, Media Optimization, Bioprocess Control, Sensory Prediction.
- Reference substrates: HumanReference, CHOReference, CrossSpecies. AI/ML benchmarks: Benchmarks.